% small example, last column is result, first columns define combinations
DATA = [1 2 4 ; 1 3 15 ; 1 2 6 ; 1 2 8 ; 1 3 25]
[UniqueCombis, ~, IDX] = unique(DATA(:,1:size(DATA,2)-1), 'rows')
% now you can use IDX to pick from the last column of DATA
for k = 1:size(UniqueCombis,1)
tmpResult = DATA(IDX==k,end) ;
disp(sum(tmpResult))
end
% count how many times each combi is present in DATA
N = accumarray(IDX,1)
disp([UniqueCombis N(:)])
% etcetera ...
