Removing comas from the text file

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Anusha
Anusha 2013-12-4
I have a text file containing some numbers separated with coma.How can I remove those comas. Example: data.txt={1,2,3,4.........}.Is there any method to remove those comas?
My text file when loaded to matlab is 2517x1001 matrix.
Kindly respond

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