Change 1:
Each element of the 2nd row is a cell array. And each of those cell arrays has two elements (1x2 dimension). Each of those two elements is in and of itself a MATLAB double variable. The way you have constructed it, you have six separate double variables, [1], [2], [3], [4], [5], [6], that are stored inside of three cell arrays that are themselves stored inside of a single cell array.
Change 2:
Each element of the 2nd row is a double array. And each of those doubles arrays has two elements (1x2 dimension). The way you have constructed it, you have three separate double variables (each 1x2), [1 2], [3 4], [5 6], that are stored inside of a single cell array.