You have a 10000x8 table. The first seven columns (10000x7) data is all the possible combinations of the seven input variables. For example, 2x5x2x5x2x5x10, a total of 10000 combinations.
You need to do a reshape() to make the last column 10000x1 data into a 2x5x2x5x2x5x10 matrix. Then use the n-D lookup table block to implement the lookup. The dimension would be 7.
It certainly is possible (dorable). You just need to make the data into the right format, the matrix mentioned above, and collect the breakpoints for all those seven input variables. For example, if the possible value for the first input varialbe is 10 and 100, then the breakpoints would be [10,100]. If the possible value for the second input variable is 5,4,3,2,1, then the breakpoints would be [1,2,3,4,5] (the value needs to be incremental).
The Matrix data needs to be arranged correctly according to the breakpoints.