Structural Identifiability with GenSSI

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Elisa
Elisa 2024-1-23
评论： Elisa 2024-1-23
I am dealing with a PBPK model in Simbiology. I have two parameters that, when both are modified even of orders of magnitute, the simulation remains exactly the same. I figured I have some issues with identifiability. I found that GenSSI is a useful tool that can provide some insights on the structural identifiability of the model's parameters. However, I cannot understand how to import the Simbiology-based model in such a way that I can use this program. Can somebody provide suggestions/tutorial?
  2 个评论
Rick Paxson
Rick Paxson 2024-1-23
I have never used GenSSI, or heard of it so thanks for pointing it out, but a brief look at it suggests they import SBML formatted files. If you have not tried that already, you can export your SimBiology model to SBML and try GenSSI.
Let us know if this works for you or if you have other questions.
Elisa
Elisa 2024-1-23
It seems like it's the only way indeed! I will try it and keep this discussion updated.

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