How to search nucleotide sequences with regexp?

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Erick Alejandro 2016-11-24

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https://ww2.mathworks.cn/matlabcentral/answers/313731-how-to-search-nucleotide-sequences-with-regexp

Hello everyone,

I am trying to search a huge list of 23 322 DNA sequences for this sequence:

XTTATTATTATTATTATTATTATTY

Where T and A are the usual bases, and I want X and Y to be A, C, T, or G, length 1. I am looking for this (TTA)7TT repeat core sequence and trying to find what are the bases immediately flanking it.

So I am using the regular expression:

[ACTG]{1,1}TTATTATTATTATTATTATTATT[ACTG]{1,1}

And I get 30 results. When I search for the flanking residues manually and sum up those results, using regular expressions like this:

ATTATTATTATTATTATTATTATTA

GTTATTATTATTATTATTATTATTG

CTTATTATTATTATTATTATTATTC

TTTATTATTATTATTATTATTATTT

and so on, I get 47 results. The first regular expression should be able to find all of the results in one go but apparently it does not. So I think I have made an error in constructing my first regular expression, because it is not finding all of the results. If there are any regular expression masters out there, I would greatly appreciate your help.