find index of points in meshgrid under the line

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I have 2D mesh grid of 501*2001. I want to get indices of values for the grid points in straight line to change the values of grid amplitude as shown in figure. Capture.JPG

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KSSV
KSSV 2019-4-23
Read about knnsearch. You will get the the required/ nearest indices for the given line from the grid.
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Abhishek Saini
Abhishek Saini 2019-4-23
Let me rephrase my question. I think i was not clear in my question.
I have 2D meshgrid of size 501x2001. Now what I would like to do is to change the value of grid in a linear form in a straight line manner. So that If I use imagesc it will show two different values.
I know the cordinates of line where I have to change the values but I want to get the values in between the two end cordinates to get all the index.

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