Bispecific Protein Degrader PK-PD Model for SimBiology

版本 1.0.2 (161.4 KB) 作者: Derek Bartlett
SimBiology project file for a published PK-PD model for bispecific protein degraders
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更新时间 2023/5/31

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The SimBiology model described in the following publication:
Bartlett DW, Gilbert AM. A kinetic proofreading model for bispecific protein degraders. J Pharmacokinet Pharmacodyn. 2021;48(1):149-163. doi:10.1007/s10928-020-09722-z
Please note that some of the included visualizations require the "gridfit" routine written by John D'Errico: Surface Fitting using gridfit (https://www.mathworks.com/matlabcentral/fileexchange/8998-surface-fitting-using-gridfit), MATLAB Central File Exchange.

引用格式

Bartlett DW, Gilbert AM. A kinetic proofreading model for bispecific protein degraders. J Pharmacokinet Pharmacodyn. 2021;48(1):149-163. doi:10.1007/s10928-020-09722-z

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创建方式 R2022a
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版本 已发布 发行说明
1.0.2

Modified for compatibility with SimBiology R2022a and newer. The initial release version 1.0.0 was created with SimBiology R2018b and will give errors in the custom visualization programs when run in newer versions of SimBiology.
1.0.1

Modified for compatibility with SimBiology R2022a and newer. The initial release version 1.0.0 was created with SimBiology R2018b and will give errors in the custom visualization programs when run in newer versions of SimBiology.
1.0.0