SigProfiler

Framework for Deciphering Mutational Signatures from Mutational Catalogues of Cancer Genomes

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引用格式

Ludmil Alexandrov (2026). SigProfiler (https://ww2.mathworks.cn/matlabcentral/fileexchange/38724-sigprofiler), MATLAB Central File Exchange. 检索时间: .

类别

在 Help Center 和 MATLAB Answers 中查找有关 Genomics and Next Generation Sequencing 的更多信息

一般信息

MATLAB 版本兼容性

  • 与 R2017b 及更高版本兼容

平台兼容性

  • Windows
  • macOS
  • Linux
版本 已发布 发行说明 Action
2.5.1

Support and updates for SigProfiler are discontinued. Please use our much better performing Python tool, named, SigProfilerExtractor, for extracting mutational signatures is now available at: https://github.com/AlexandrovLab/SigProfilerExtractor

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2.5.1-8

Updated description

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2.5.1-7

Update

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2.5.1-6

Update

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2.5.1-5

Update

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2.5.1-4

Update

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2.5.1-3

Update

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2.5.1-2

Update

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2.5.1-1

Minor fixes

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2.5.1-0

Fixed small release bugs.

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2.5.0

Fixed small bugs that affected SigProfiler execution using MATLAB installed on Microsoft Windows operating systems. Updated SigProfilerSingleSample to allow input and output in text format.

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2.4.1

Updated documentation.

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2.4.0

Added capability to perform analysis from text/CSV input files. Output is expanded to also contain text/CSV output files. Minor modifications to the plotting functions. Updated documentation.

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2.3.2

Minor updates to the documentation.

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2.3.1

Minor bugs fixed.

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2.3.0

Several plotting bugs were fixed. Minor updates to the documentation. A new version of SigProfilerSingleSample has been released.

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2.2.0

Updated SigProfilerSingleSample for a novel set of signatures. Update example.

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2.1.0

Added sparse assignments of the activity of mutational signatures in the tool SigProfilerSingleSample.

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2.0.0

Added sparse assignments of the final activities of mutational signatures. Added another plotting function to one of the examples. Updated documentation and comments in the code.

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1.9.0

Provided code and an example for performing hierarchical signatures analysis.

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1.8.0

The framework now includes a tool for assigning known mutational signatures in individual samples. An example for running the tool on a set of bladder cancer exomes is provided.

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1.7.1

Updated description.

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1.7.0

Updated name, description, and documentation.

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1.6.0

The framework was updated to improve its accuracy for extracting mutational signatures. Bugs to parallel execution were fixed. Completely new set of examples was provided. The format of output files was changed. Archive folder has been updated.

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1.5.0

The code was updated to work with R2017b. The previous version was using commands from R2008b which were deprecated in recent MATLB releases. Several minor bugs have also been fixed.

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1.4.0

Data has been separated in folders based on publications. Functions for plotting individual samples have been provided.

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1.2.0

Several minor plotting bugs were fixed. Additionally, we have included extensive cancer genomics data allowing mutational signature analysis of multiple cancer types.

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1.0.0

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