Cannot segment an image of brain into white and grey matter

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My aim is to extract both white and grey matter from the image ( http://imgur.com/6Zd04W1).
Tried many tools from MATLAB file exchange and some other softwares (MIPAV, SPV, etc.) so far to no avail. It looks like both white and grey matter have quite low contrast. Can anyone suggest some tricks to extract both white and grey matter?

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Image Analyst
Image Analyst 2014-1-19
You will find algorithms for that here: http://iris.usc.edu/Vision-Notes/bibliography/contentsmedical.html#Medical%20Applications,%20CAT,%20MRI,%20Ultrasound,%20Heart%20Models,%20Brain%20Models Since I doubt simple thresholding will do it, you're on your own. We can't help with such complicated algorithm development here.

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