about SNR sand PSNR calculation

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Hi.
I have a reference image(capsule endoscopy) which has Gaussian noise. I want to filter this image to make it noisefree and finally want to calculate its SNR and PSNR.How to resolve this problem. Thanx in advance.

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Image Analyst
Image Analyst 2014-3-7
See my PSNR demo, attached.

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