MATLAB has third-party toolboxes and MATLAB File Exchange submissions that are designed to handle CFD applications. While I am not sure if these third-party modules are suited to your specific workflow, you can check the following pages and confirm:
https://www.mathworks.com/matlabcentral/fileexchange/72640-cfdtool-matlab-cfd-simulation-gui-toolbox
Since these tool are third-party, we cannot guarantee the validity of their CFD simulation results or provide support.
You can also check out the below related resources published by Mathworks: