It appears that you installed MATLAB to your user's directory, rather than the default Program Files directory (where most applications install on Windows PCs).
You should install MATLAB in the default directory, or possibly in a MATLAB folder on your main disk, but certainly not in a user directory that you then try to use for saving and manipulating your own files in. Application installation folders are usually protected for security and robustness reasons, so the fact that you are trying to work in an application installation directory is a sign of massive weakness and vulnerability on your PC. MIxing your personal data files and application files is a terrible idea.
By the way, this applies to all applications, not just MATLAB: in general they should be installed to your Program Files folder (or similar) and you should NOT be working in the installation folder (or any folder under it).
