Finding intensity of region inside a circle from image

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Hi all, I have this image below of a circular bead (also attached):
I would like to calculate the average intensity of all pixels inside this circular bead, I have read things about regionprops but it unfortunately does not apply in my case as my bead isn't super bright at the centre. Any help would be greatly appreciated!

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DGM
DGM 2021-11-26
编辑:DGM 2021-11-26
Something like this:
A = rgb2gray(imread('Bead_pic.png'));
mask = A<100;
mask = imfill(mask,'holes') & ~mask;
% show the thing for sake of clarity
imshow(uint8(double(A).*mask))
avggrayval = mean(A(mask))
avggrayval = 141.7906

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