Yes, there is a MuPad call named "is" that will test a condition. It is not strictly constrained to numeric relations: it can test properties such as data types, and when assumptions have been applied, it may be able to decide relationships between expressions that involve symbolic variables. Most of the time, though, expressions that involve symbolic variables without assumptions are not decidable, and is() will return false for those cases.
Coding the relational expression at the Matlab level can be a problem, so you usually end up having to express it as a string and using subs() to transfer the values from the Matlab engine to the symbolic engine.
