Segment the foreground from the background
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How can i segment foreground and background from the attached images? When i do threshold method the nucleus (marked in red) and the debris (the circled orange region) is wrongly identified. The background colour is not same for the images, so colour based foreground and background detection will also not give desired result. Please can someone suggest which method can be used to segment the debris from the images so that i can segment the nucleus correctly.

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