You may import data from Excel as signals in Simulink using the "From Spreadsheet" block - https://www.mathworks.com/help/simulink/slref/fromspreadsheet.html.
Alternatively you can also programmatically import data from excel file into MATLAB using "readtable" function - https://www.mathworks.com/help/matlab/import_export/read-spreadsheet-data-into-table.html.