How to extract skull from MRI image?

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ELI 2015-2-19

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https://ww2.mathworks.cn/matlabcentral/answers/179240-how-to-extract-skull-from-mri-image

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Hi,

I'm trying to extract only the skull from the image. The problem here is that a little tumor between the eyes is somehow connected to skull and when I remove the skull by threshold, the tumor goes with the skull. The center of the tumor is in pixel(395,252) in the attached 3d data.