Vlad - assuming that you are using GUIDE to create your GUI, suppose your five popup menus are named popupmenu1, popupmenu2,..., popupmenu5. If we assume that only numeric data has populated each of your popup menus, then the callback for your push button would look something like
function pushbutton1_Callback(hObject, eventdata, handles)
% get the list of items in the first popup menu
menu1List = get(handles.popupmenu1,'String');
% get the selected item in the first popup menu and convert to a number
menu1Item = str2num(menu1List{get(handles.popupmenu1,'Value')});
You would then just repeat the above code for the remaining four popup menus and do whatever operation you need against them.
