graphing mean and SD of time-course data (grouping based on group number and time)

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Hello,
I am trying to graph the mean and SD deviation of time-course data. I need to use the mean and SD based on the group number at each time point. I will then overlay this time-course data with some simulations I've performed. Can anyone help provide me with the code to do this?
Thanks in advance!

回答(1 个)

Pavan Sahith
Pavan Sahith 2023-10-5
Hi Brett,
As per my understanding, you want to plot the mean and standard deviation of data based on group number at each time point. Additionally you want to overlay this time-course data with some simulations.
  • So, I assumed a simple time-course data example with 10 elements and some sample simulation data for better understanding.
time = [1 1 2 2 3 3 4 4 5 5]; % Time points
group = [1 1 1 2 2 2 3 3 3 4]; % Group numbers
data = [10 12 9 11 8 10 7 9 6 8]; % Time-course data
Which means,
at time=1, data =10 if it is from group =1 (mapping 1st element in all 3 arrays)
at time=3, data =8 if it is from group =2 (mapping 5th element in all 3 arrays)
uniqueGroups = unique(group);
uniqueTime = unique(time);
%initializing the mean and std matrices with all 0s
meanData = zeros(numel(uniqueGroups), numel(uniqueTime));
stdData = zeros(numel(uniqueGroups), numel(uniqueTime));
  • To find the mean and standard deviation you can use mean() and std() , Please refer the following MathWorks Documentation links for more information
% populating the matrices using mean and std functions
for i = 1:numel(uniqueGroups)
for j = 1:numel(uniqueTime)
idx = group == uniqueGroups(i) & time == uniqueTime(j);
meanData(i, j) = mean(data(idx));
stdData(i, j) = std(data(idx));
end
end
  • To plot mean and standard deviation based on groups at each time point , you can use errorbar as standard deviation is defined as a measure which shows how much variation (such as spread, dispersion, spread,) from the mean exists. For more details, please refer the following MathWorks Documentation link on errorbar-https://in.mathworks.com/help/matlab/ref/errorbar.html
figure;
hold on;
for i = 1:numel(uniqueGroups)
errorbar(uniqueTime, meanData(i, :), stdData(i, :), 'o-', 'LineWidth', 1.5);
end
% labelling the axes and setting a title
xlabel('Time');
ylabel('Data');
title('Mean and Standard Deviation of Time-Course Data');
grid on;
  • To overlay the simulations ,please refer to the following sample code which is using sample simulation data to plot.
% Overlay simulations with sample data
simulations = [9.5 11 8.5 10.5 7.5]; % Simulated data
timeSimulations = [1 2 3 4 5]; % Time points for simulations
groupSimulations = [1 2 3 4 1]; % Group numbers for simulations
for i = 1:numel(uniqueGroups)
idx = groupSimulations == uniqueGroups(i);
plot(timeSimulations(idx), simulations(idx), 'r--', 'LineWidth', 1.5);
end
legend('Group 1', 'Group 2', 'Group 3', 'Group 4','Simulations');
Please execute the MATLAB code to see the plot for the given sample data.

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