When you actually perform the fit, you typically want one row in your data that describes each distinct dose event. (It is also possible to set up separate doses and/or variants to use during fitting, but I don't think you need to do that here.)
SimBiology can understand the ADDL and II columns when importing data in the NONMEM format and convert that into a table that's appropriate for fitting. (You can read more about NONMEM support here.) As shown here, you can either rely on the default names for NONMEM columns, or you can explicitly tell SimBiology that ADDL is your DoseRepeatLabel and II is your DoseIntervalLable. When you import the data, SimBiology will convert this one row with ADDL and II information into one row per dose event.
I hope that makes sense. If you need more details, just let me know whether you're working at the command line or in the SimBiology Model Analyzer app (or both!), and what version of MATLAB you're using.
-Arthur
