Hi,
The ePWM block does not require any interrupt. However, you can specify when and how CMPA and CMPB Registers update their values. Please see below pic:
![](https://www.mathworks.com/matlabcentral/answers/uploaded_files/1385264/image.png)
For more info you can visit: Generate enhanced Pulse Width Modulated (ePWM) waveforms - Simulink - MathWorks India
Hope it clarifies your query.
Regards,
Vishwa