Payload release from ADC in Simbiology

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Yosuke Nakatani
Yosuke Nakatani 2023-10-23
评论： Yosuke Nakatani 2023-10-23
If in the case one ADC release 4 molecules of payload at once (and ADC change to the mAb), how to describe this reaction in diagram of Simbiology?

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回答（1 个）

Jeremy Huard
Jeremy Huard 2023-10-23
Dear Yosuke,
SimBiology supports setting stoichiometry coefficients in reactions.
If you use the Model Builder App, you can first create a reaction as usual and then add stoichiometry coefficients manually by editing the Reaction property:
SimBiology will then generate the ODEs accordingly:
I hope this helps.
Best regards,
Jérémy

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