Hello zhang,
The error you are encountering is often due to hardware or software incompatibility between the real-time kernel and either the operating system or the computer's mainboard, which results in the inability to allocate a hardware timer. To ensure compatibility between the real-time kernel and the latest operating system updates, please consider using the most recent releases of MATLAB and Simulink Desktop Real-Time, as improvements are continually made with each new version.
You might find it helpful to refer to the MATLAB Answers thread below, which discusses a similar issue:
Hope this helps.