Dynamic contrast agent in MRI

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MARINA 2024-10-24，14:57

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评论： William Rose 2024-10-25，13:34

Hi everyone.

I just wondering if someone has worked with perfussion MRI images. I have a DCE experiment in kidneys and I would like to work with matlab to obtain the parameters of the model (one compartment, two compartment...), I want to work with Simbiology

Thanks a lot.

Regards

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Answer 1

William Rose 2024-10-24，16:18

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编辑：William Rose 2024-10-24，16:19

@MARINA,

[Edit: fix spelling.]

I have worked with MRI images, but not with perfusion images. I have also worked with fitting compartmental models. But not with Simbiology.

See Zollner et al, 2021 for a good description of analysis procedures. Zollner et al assume the user has certain non-Matlab software packages. Even if you don't have those packages, Zollner's chapter is useful.

To avoid re-inventing the wheel, check out the Matlab file exchange submissions for MRI imaging and for perfusion model fitting. For example, MP3 Medical Imaging Toolbox; 4D medical image de-noising; 4D data exploration; View4D; and two packages by excellent authors who have helped many of us on Matlab Answers: Image Manipulation Toolbox by @DGM and Image Segmentation Tutorial by @Image Analyst.

References:

Dynamic Contrast Enhancement (DCE) MRI–Derived Renal Perfusion and Filtration: Basic Concepts, Pertersen et al., 2021.

Dynamic Contrast Enhanced (DCE) MRI-Derived Renal Perfusion and Filtration: Experimental Protocol. Irrera et al., 2021.

Analysis Protocol for Dynamic Contrast Enhanced (DCE) MRI of Renal Perfusion and Filtration. Zöllner et al., 2021.

Good luck with your research.