integration tolerance has not met
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Hi
I encountered an issue in implementing the growth rate of the tumor. In the following equation, both tumor carrying capacity and tumor volume are species
(d/dt)TumorVolume = r * TumorVolume * log(TumorCarryingCapacity/TumorVolume)
I received a message error that the integration tolerance has not met. I believe it is because tumor carrying capacity and tumor volume are species and they have to be that.
How would I solve this?
Appreciate your help
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Arthur Goldsipe
2025-4-17
0 个投票
If you can share your model or other reproduction steps, then we can likely offer better advice. In the absence of those details, one thing I notice is that the rate equation you provide could easily result in non-finite values. For example, if TumorCarryingCapacity is ever 0, then the log term will be -inf (assuming a positive, finite value for TumorVolume). If r or TumorVolume is also 0 at the same time, then the rate will be NaN.
You could use the SimBiology Model Debugger to step through your simulations to see if non-finite values appear and determine what their source is.
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