Parameter estimation for an epidemic model

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I have an epidemic model:
function ypsirid = ypsirid(t,y)
global q m b r
ypsirid(1) = q - m*y(1) - b*y(1)*y(2);
ypsirid(2) = (b*y(1)*y(2)) - (m+r)*y(2);
ypsirid(3) = (r*y(2)) - m*y(3);
ypsirid = ypsirid(:)
I would like to estimate two parameters - b and r for this model. Can anyone kindly suggest the easiest possible method to do so using MATLAB.

采纳的回答

Torsten
Torsten 2015-8-3
As a guideline, take a look at
There, parameters of a Monod kinetic have been fitted to measurements.
Best wishes
Torsten.

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