Hey Benjamin,
You can programmatically change the signal names in the case of Bus Creator block but if your model uses Bus Selector block as well then you need to manually select the updated name of the signal in the Bus Selector block. This is because the Input Signals in Bus Selector is a read only object and modifying it programmatically produces an error.
For more information regarding this query, please refer to the following MATLAB Answer:
I hope this helps!