It's a very good idea to try to set up your optimization so all the parameters have approximately the same impact on the objective function. For instance, if one parameters is on the order of 10^2, divide it by 100, while if it's on the order of 10^-3, multiply it by one thousand.
Scale or ScaleMesh can help with this, but it's a better idea to just properly scale your problem in the first place.
