Hi Fiona,
Have a look at the following documentation page for interp1. This command allows you to create a 1-D lookup table with your choice of interpolation and extrapolation methods in MATLAB. You can also have a look at 'interp2', 'interp3' and 'interpn' commands for your reference.
In this case, I think that interp2 command will suit your requirement. So, if you see the function signature,'V' will be the data, which you have imported from the EXCEL file and you will need to give coordinates of the sample points as X and Y. Please have a look at the examples given in documentation page for better understanding.
Abhisek