In SimBiology, is there any way to fit multiple data sets to the model with a single set of parameters? How can I do this using Simbiology desktop or coding?

Question

Sean Quinn 2018-1-30

0
链接

此问题的直接链接

https://ww2.mathworks.cn/matlabcentral/answers/379867-in-simbiology-is-there-any-way-to-fit-multiple-data-sets-to-the-model-with-a-single-set-of-paramete

回答： Arthur Goldsipe 2018-2-1

My data sets result in a signal for the output but one of the initial conditions (or states) is different for each data set.

0 个评论
显示 -2更早的评论隐藏 -2更早的评论

请先登录，再进行评论。

请先登录，再回答此问题。

Answer 1

Arthur Goldsipe 2018-2-1

0
链接

此回答的直接链接

https://ww2.mathworks.cn/matlabcentral/answers/379867-in-simbiology-is-there-any-way-to-fit-multiple-data-sets-to-the-model-with-a-single-set-of-paramete#answer_302937

I described a solution to a similar problem here. But let me summarize here. You can fit the data using the command-line function sbiofit with the pooled option, or with the equivalent task in the SimBiology desktop. You will need to implement the different initial conditions as different doses for each condition and then use the Pooled option so that you estimate a single set of parameters for all conditions.