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Noise reduction for microscopic images

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Sam Lee
Sam Lee 2018-3-29
关闭: John D'Errico 2018-3-29
I have these microscopic images that need to be analyzed based on the size, shape and color of the nuclei in the cells. I tried reducing the noise using a Median Filter, but when i binarized the image it looked terrible. What is the best method to reduce the noise in these images before analysis?
Image sample:
Note: the green spots are the ones being analyzed. The red color does not contribute to the analysis.
Thanks

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