Here's a simple example on how to do achieve this
s = table([1; 2; 3], [4; 5; 6], 'VariableNames', {'A', 'B'});
% Create the new table
t = array2table([7; 8; 9], 'VariableNames', {'A'});
% Replace column A in table s with table t
s.A = t.A;
disp(s)
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