How does SimBiology calculate the "lambda" in NCA?

2018 10 16
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更新时间：2018 10 16
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I was wonder that How does SimBiology calculate the "lambda" in NCA?
When I use WinNonlin, I can choice the weighting option in linear regression (ex. unweighted, 1/y, 1/y^2).
Although SimBiology doesn't provide the weighting option, I think that Simbiology uses any one of above.
Thank you.

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Arthur Goldsipe
Arthur Goldsipe 2018-10-16

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Hi,
Currently (as of R2018b), SimBiology's NCA uses linear regression with all of the points weighted equally. I'm guessing that's what you would call "unweighted."
-Arthur

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