if ndims(YourArray) == 2
blocks2x2 = mat2cell(YourArray, 2 * ones(1,128), 2 * ones(1,128) );
else
blocks2x2 = mat2cell(YourArray, 2 * ones(1,128), 2*ones(1,128), size(YourArray,3) );
end
(Really this can be done with just the second of those assignments without an 'if', but splitting the case permits you to avoid a warning.