Remove duplicate rows based on subset of row elements

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Hello everyone,
I tried to find a similar problem - relatively simple I believe - but I could not find a solution. If, for instrance, I have a matrix such as
A = [1 1 1 100; 2 2 2 200; 3 3 3 300; 1 1 1 500]
how can I remove from A the fourth row based on the fact that only the thee first elements of the that row are identical to the three elmenets in the first row?
Also, what if I have
A = [1 1 1 100; 2 2 2 200; 3 3 3 300; 1 1 1 500; 1 1 1 600]
and, again, I just want to keep the first row?
Thank you for your help.

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madhan ravi
madhan ravi 2019-3-5
编辑:madhan ravi 2019-3-5
A(unique(A(1:3),'rows'),:)
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