Like the error message mentions, the port is already being used by another application ( or by an earlier run of your MATLAB script) . You might need to first restart your machine to free up the port ( or kill the process that is listening on that port).
You can enable port sharing to allow multiple UDP sockets to bind to the port :
u1 = udp(HOST1, SOURCE_PORT1,'Localport' ,LOCAL_PORT1);
u1.EnablePortSharing = 'on';
Also make sure to close the UDP socket at the end to avoid running into such problems :
fclose(u1);