Try this: You may use the Import Data Tool to do it graphically. [Click: 'Home' Tab > 'Variable' section > 'Import Data' icon]. In the Import Tool, you may modify the selected area to just the first two columns. Please select the output type too, to Table/ColumnVectors... etc. For full functionality, refer to the doc below:
If you're writing a script to do this, have a look at importdata, textscan, fscanf and similar functions. You may search the documentation for the same.
Alternatively, you may read all columns using importdata and then select out only the first two after that:
myData = importdata('YouFileName.txt');
myData = myData([1 2], :);
