Hi Hanwen,
If I understand you correctly, you could follow one of two routes:
- use three separate Repeat Doses. One for day 1, one for day 8, one for day 15. Then apply all three doses together in your simulation. This would be the best solution if you want to repeat the Q3/4W beyond 28 days, e.g. the 15 cycles you describe
- use a single Schedule Dose and have a line for each dose. You could do this manually but that would be tedious for 15 cycles. You can make your life easier by click on "Editor" (circled in the attached screenshot) and give entries in MATLAB code for "Time", "Amount" and "Rate" (leave Rate empty if there is no associated rate with the dose amount). E.g.
time = repmat([1 8 15],1,15)
amount = repmat([100 200 300],1,15) % assuming dose at t = 1 is 100, t=8 is 200, t = 15 is 300.
rate = repmat([200 400 600],1,15)
Option 2 is probably the preferred solution if you only want a single dose object to deal with (as opposed to the 3 repeat doses from option 1.
