License issues are best addressed by a call to Technical Support.
I'd guess that if this was working yesterday, though, the first person you should contact is the person who set it up for your department. Sounds like the license may be incorrect or the license file has been altered:
From the documentation for the license server (<http://www.gtx.com/support/faqs/license/acresso/FLEXnet_Licensing_Error_Codes.asp>)
-25 License server system does not support this version of this feature.
-147 Bad V80_LK signature.
