how to generate (multiple) realisations using Gillespie Algorithms
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Hello, I would like to simulate this reaction
a->X
X-> X
at rates c. here is a code was written by Desmond Higham and I tried to adopted it to this reaction.
I would like to simulate different realisations . Could you please shed a light on this.
Your help is highly aprrecaited.
clf
clear all;
clc
rand('state',100)
%stoichiometric matrix
V = [1 -1];
%%%%%%%%%% Parameters and Initial Conditions %%%%%%%%%
nA = 6.023e23; % Avagadro's number
vol = 1e-15; % volume of system
X = zeros(1,1);
X(1) = 100; % molecules of substrate
c(1) = .4; c(2) =.1; c(3)=8; c(4)=.3;
t = 0;
tfinal = 100;
count = 1;
tvals(1) = 0;
Xvals(:,1) = X;
while t < tfinal
a(1) = c(1);% calculate propensity functions
a(2) = c(2)*X(1);
asum = sum(a);
j = min(find(rand<cumsum(a/asum))); % select which reaction
tau = log(1/rand)/asum; % select time
X = X + V(:,j); %update X
count = count + 1;
t = t + tau; %Update time
tvals(count) = t;
Xvals(:,count) = X;
end
%%%%%%%%%%% Plots %%%%%%%%
L = length(tvals);
tnew = zeros(1,2*(L-1));
tnew(1:2:end-1) = tvals(2:end);
tnew(2:2:end) = tvals(2:end);
tnew = [tvals(1),tnew];
%
Svals = Xvals(1,:);
ynew = zeros(1,2*L-1);
ynew(1:2:end) = Svals;
ynew(2:2:end-1) = Svals(1:end-1);
plot(tnew,ynew,'g-')
hold on
5 个评论
yamen alharbi
2021-1-3
Star Strider
2021-1-3
Relevant information on the Gillespie algorithm would be helpful. I didn’t find anything that related to it that had sufficient detail when I did an Interweb search several days ago. (Obviously, I have no prior experience with it.)
yamen alharbi
2021-1-3
Star Strider
2021-1-3
The only one that appears to be accessable is the SIAM paper. I’ll download it now and read it later. (The first is behind a paywall, the second offers only short descriptions and no links to other information.)
yamen alharbi
2021-1-3
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