Method to include insertions in compact alignment from BioMap object?

1 次查看（过去 30 天）

显示更早的评论

Turner 2013-5-25

0
链接

此问题的直接链接

https://ww2.mathworks.cn/matlabcentral/answers/76979-method-to-include-insertions-in-compact-alignment-from-biomap-object

关闭： MATLAB Answer Bot 2021-8-20

Hi all,

I'm working with a BioMap object containing 50bp sequencing reads from a BAM file. My goal is to retrieve a full genome sequence from the BioMap. So far, I know how to use getCompactAlignment to get a memory-friendly version of an alignment that can be converted into a consensus sequence. I've mastered how to handle deletions, but getCompactAlignment does not account for insertions, and actually removes them from the alignment. Is there another method to generate a compact alignment or direct consensus sequence from a BioMap that includes insertions?