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Generate dose response curve with Simbiology

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Kieran 2013-6-11

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https://ww2.mathworks.cn/matlabcentral/answers/78750-generate-dose-response-curve-with-simbiology

Hey,

I know that I can run a scan over various values of a species using the scan task. However, I'd like to generate dose response curve based on the steady state of these data.

for example, I'd like to scan the concentration of a cooperative Transcription Factor that binds to a promotor. and plot the steady state expression of that promotor as a function of the concentration.

Is that possible? Something like this:

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回答（1 个）

Ingrid Tigges 2013-6-12

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https://ww2.mathworks.cn/matlabcentral/answers/78750-generate-dose-response-curve-with-simbiology#answer_88554

Yes, it is possible. Have a look at this entry from the file exchange: http://www.mathworks.com/matlabcentral/fileexchange/35995-using-simbiology-for-mechanism-based-pkpd-modeling-in-preclinical-discovery

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Computational Biology SimBiology Simulation Scan Parameter Ranges

在 Help Center 和 File Exchange 中查找有关 Scan Parameter Ranges 的更多信息

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SimBiology

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