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How to automatically change the active state of zero-order uptake
I have a species which is absorbed in a zero-order manner. I want to model the reaction rate as "UptakeRate*ActiveState". So I c...
3 years 前 | 0
提问
Cannot export plots from SimBiology Model Analyzer
Dear all, I almost cannot export plots of a simulation programme from SimBiology Model Analyzer. I only succeeded several times...
3 years 前 | 0 个回答 | 0
0
个回答Discussion
Why assume Cup is equal to Cub
Hi, all Recently I read the book "Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations: Principles, Methods...
5 years 前 | 0
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Question about using an Exponential within a rule using Simbiology
Hi, Brett, As what you mentioned, I think the your rule is "Rule_6=exp(m*log(Concentration/Concentration0)+b)". And I think you...
Question about using an Exponential within a rule using Simbiology
Hi, Brett, As what you mentioned, I think the your rule is "Rule_6=exp(m*log(Concentration/Concentration0)+b)". And I think you...
5 years 前 | 2
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提问
Can I generate MATLAB code for a PK simulation built with SimBiology APP?
Hi, all I have built a PBPK model with SimBiology APP and now I want to know its equivalent MATLAB code. Can I generate the cod...
5 years 前 | 1 个回答 | 0
1
个回答提问
What does this message mean, "CVODES returned -4..." ?
Hi, all When I use SimBiology Analyzer, I get this message: This would happen when I use a customized function like: functi...
5 years 前 | 1 个回答 | 0
1
个回答提问
How to correctly compile a function containing variables with dimension and call it in SimBiology
Hi, all I want to calculate the intestinal solubility of drug according to intestinal cyclodextrin concentration in a SimBiolo...
5 years 前 | 1 个回答 | 0
1
个回答Discussion
How to properly record absorbed dose fraction?
Hi, all friends, I want to record the fraction of drug absorbed in each intestinal segment, so I define a set of parameters w...
5 years 前 | 0
Discussion
Be confused by a NCA result
Hi, all friends I am dealing with a confusing NCA result. As this result shows, AUC_infinity=0.8537 (μg*h/mL), DM=1 (mg). C...
6 years 前 | 0
Discussion
Can SimBiology change value of parameters in reaction automatically by specified dimension?
Hi, all friends If I define a parameter, like solubility with dimension of *milligram/milliliter* and I want to refer it in a...
6 years 前 | 0
Discussion
Questions on intestinal transit rate in "Generic SimBiology PBPK model"
Hi, all friends I am working on building a oral model with "Generic SimBiology PBPK model" and meet some problems about intes...
6 years 前 | 0
Discussion
Problem on "Generic SimBiology Physiologically-based Pharmacokinetic (PBPK) model"
Hi, fellows, I am a new user of MATLAB and SimBiology. When I open the "Generic SimBiology Physiologically-based Pharmacokine...
6 years 前 | 0
