Sietse Braakman, PhD, MathWorks
Drug discovery and development software spans a spectrum of modeling and analysis tools. You will learn about the new features in SimBiology® that help span modeling and simulation workflows from pharmacokinetic (PK) to quantitative systems pharmacology (QSP) modeling.
• Visualizing confidence intervals on parameter estimates to determine whether model parameters are identifiable given a set of data
• Performing noncompartmental analysis (NCA)
• Computing NCA parameters on simulation data to optimize dosing schedules and amounts relative to target PK parameters
• Running numerous model evaluations with cluster computing on the cloud to explore model response to biological variability