If you want your file to be smaller, you probably need to change the data type. A normal number in Matlab (stored as a double) will require 64 bits to store. If you only deal with integer values that are small enough, you could try int8 or uint8. If you have a wider range of values but still want a size reduction, you could also consider converting your data to single, which only uses 32 bits.
But how were you planning to do anything at all without coding? That sounds the same to me as if you would ask how to use Matlab without mouse and keyboard.
