how to select small dark part of an gray image ?

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I am written an application that select cells in the liver carcinogens, and I'm having trouble identifying small parts infected with cancer Is there a algorithm to do so. Note that the picture is image scan of the liver.
this problem is like a problem that disused in Recorded Webinars(Automating the Analysis of Life-Sciences Data with MATLAB) but in gray.
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Walter Roberson
Walter Roberson 2012-2-5
http://www.mathworks.com/matlabcentral/answers/7924-where-can-i-upload-images-and-files-for-use-on-matlab-answers

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Image Analyst
Image Analyst 2012-2-5
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