How can Simbiology dosing be administered continuously instead of discretely?
6 次查看(过去 30 天)
显示 更早的评论
MathWorks Support Team
2017-7-12
编辑: MathWorks Support Team
2024-4-18
How can dosing be administered continuously instead of discretely?
Here is what I am currently trying:
-Start the Simbiology App
-Add a Linear {Clearance, Volume} Infusion Model
-Add a "schedule dose" to the model under "Dose_Central"
-Double click green table next to 'dose_1'
-Click "Editor..." button
I am unsure of how to specify the dosage so that it is continuous instead of providing a discrete amount at each time. I have looked through some documentation on dosing but was unclear if there was an easy way to change the 'rate' to accomplish this.
采纳的回答
MathWorks Support Team
2024-4-18
编辑:MathWorks Support Team
2024-4-18
There are two ways to implement continuous dosing:
1) Use a repeat or scheduled dose with just one dose starting at t=0. You can set the 'rate' parameter to the rate you need and set the 'amount' parameter to a large number. This way, the total amount will never be reached and the dose is given continuously. Your 'amount' should be larger than 'rate*(duration of simulation)'
2) Instead of a dose object you can introduce a reaction “null -> species” reaction with a rate parameter k and mass action kinetics. This describes a continuous synthesis or dosing of “species”.
0 个评论
更多回答(0 个)
另请参阅
类别
在 Help Center 和 File Exchange 中查找有关 Simulate Responses to Biological Variability and Doses 的更多信息
Community Treasure Hunt
Find the treasures in MATLAB Central and discover how the community can help you!
Start Hunting!