line([0.2, 19.8], [1, 1], 'Color', [1,0,0]);
If you have a question about drawing a "line", look into the documentation:
docsearch line
To get the area, create a polygon at first by finding the points, where this line crosses the area. Perhaps this helps:
You can find such functions by searching in the FileExchange or in the internet. You are a long term user of the forum and should know, that you are wanted to search by your own at first.