Yes, you can use the batch command to do this. You'll need Parallel Computing Toolbox installed on your desktop MATLAB client, and MATLAB Distributed Computing Server installed on the cluster.
Instructions for configuring MATLAB Distributed Computing Server for an LSF cluster are here: https://uk.mathworks.com/help/mdce/configure-parallel-computing-products-for-supported-third-party-schedulers-pbs-pro-platform-lsf-torque.html
To set up specific options for your batch submission, you should set up SubmitArguments for your cluster object. You can do this either through the "Cluster Profile Manager", or at the command-line. Here's an example, presuming you've already set up your basic profile.
myCluster = parcluster('myLSFProfile');
myCluster.SubmitArguments = '-R rusage[mem=100]';
myJob = batch(myCluster, 'myScriptName');
This will submit myJob to your LSF cluster, to run the script called myScriptName, and it will add the specified SubmitArguments to the bsub command-line.
